After an extraction, preserving as much of the alveolar ridge as possible can make subsequent implant placement considerably more predictable. But when it comes to filling the extraction socket, clinicians now have several options.
Platelet-rich fibrin (PRF) has gained considerable interest because it is autologous and can be prepared chairside. But can PRF alone preserve the dimensions of an extraction socket as effectively as a bone graft?
Researchers searched PubMed/MEDLINE, Scopus and the Cochrane Central Register of Controlled Trials for studies comparing PRF with bone graft materials for alveolar ridge preservation. Nine studies met the inclusion criteria and were included in the analysis.
Overall, sockets treated with PRF experienced significantly greater loss of both ridge height and ridge width than those treated with bone grafts.
For ridge height, the pooled analysis showed significantly greater dimensional loss with PRF, with a standardized mean difference of 0.37. The difference was even more evident for ridge width, where PRF demonstrated significantly greater loss, with a standardized mean difference of 0.44.
This suggests that when preservation of the original ridge dimensions is the primary objective, bone graft materials may offer an advantage over PRF alone.
What happened when the graft material was standardized?
One challenge when comparing bone grafting studies is that different graft materials may produce different results.
The researchers therefore performed an additional analysis including only studies in which the same graft material—freeze-dried bone allograft—was used.
Here, the picture became slightly more nuanced.
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