Which clinical conditions could change the conclusions of Our Second Brain: More Than a Gut Feeling?

DentalReach Critical Appraisal:

Explore the enteric nervous system, gut–brain communication and the scientific basis behind describing the gastrointestinal nervous network as a second brain. Application requires confirmation of diagnosis, baseline risk, realistic benefit, alternatives, potential harm and a defined review plan.

DentalReach Clinical Contributor:

A recommendation is clinically useful only when the patient group, intervention, comparator, outcome and follow-up are clearly defined.

DentalReach Evidence Review:

Shared decision-making should cover benefit, uncertainty, alternatives, maintenance and the consequence of no treatment, especially before irreversible care.