Author : Dr Babusha Chauhan, BDS, Meerut, India
Abstract-
This study 1 was conducted to prepare a dental composite material with antibacterial activity. This type of filling material will help in caries reduction along with reduced biofilm formation. Strength of the material was maintained along with flexural properties. The prepared material show significant antibacterial activities along with strength maintenance.Aims & Objectives
The aim of this study 1 was to make a dental composite material having anti bacterial activities in it. For this montmorillonite (MMT) was loaded with chlorhexidine (CHX). To develop this small amount of MMT/CHX was added to a matrix of Bisphenol A hydroxy-methacryloxypropyl ether (BisGMA) / Triethyleneglycol Dimethacrylate (TEGDMA). This study was done to assess the drug discharge capacity of MMT 2.Methods
BisGMA/TEGDMA are mixed in equal proportion by weight to form the experimental organic matrix. The formed composite constitutes montmorillonite with or without chlorhexidine. The concentrations were maintained at 2.5%, 5% and 10% by weight. Fourier-Transform Infrared Spectroscopy (FTIR) analysis method was used to analyze degree of conversion (peak 6165 cm-1; n = 5). Three point bending test was performed to evaluate Elastic Modulus (E) and flexural properties(n=10). Inhibition test was performed against some bacteria (Staphylococcus aureus, Streptococcus mutans, and Porphyromonas gingivalis) with n=5 of each bacteria to check anti-bacterial activities. In culture media of Streptococcus mutans (n=10) a disc of composite was inserted to check the biofilm formation (BF) inhibition. Clorhexidine release was analyzed by ultraviolet (255nm) which was performed for 10 days (n=5). Mann–Whitney method was performed to evaluate degree of conversion. (n- sample size)Free for members
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