Diamond nano-particles, namely, nano-diamonds (NDs) with many promising physico-chemical properties, have been demonstrated to work as an effective antibacterial agent against planktonic cells (free-floating state).
Nanotechnology is being intensively explored nowadays to provide more efficient therapeutics as there is a constant increase in antibiotic resistance. The complex microbial communities which are the main cause for oral infections show particularly high resistance to conventional antibiotics.
In a journal article published in Biomaterials Science ("Biofilm inhibition in oral pathogens by nanodiamonds"), scientists from the Faculty of Engineering and the Faculty of Dentistry of the University of Hong Kong (HKU) revealed for the first time the inhibitory effect on oral pathogenic biofilms by high-pressure high-temperature (HPHT) nano-diamonds.
In particular, they uncovered the role of NDs in inhibiting biofilm formation and their disrupting effect on preformed biofilms in several selected orally and systemically important organisms.
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